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Vacation rentals in Clayton

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Top-rated vacation rentals in Clayton

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Apartment in Soulard

4.95 out of 5 average rating, 110 reviews

Third Floor Queen Suite w/Fitness Center (327)

Soulard apartments aren't supposed to be this luxurious! If you are searching for a place to stay in Soulard and don't necessarily want the old historic, cobblestone, 1800's theme permeating through your walls, then look no further! We confidently boast the newest and nicest apartments in Soulard. - 0.5 Mi to Molly's in Soulard - 1.5 Mi to St. Louis Aquarium - 2.0 Mi to Gateway Arch - 2.2 Mi to The City Museum - 2.1 Mi to Ballpark Village - 1.6 Mi to Enterprise Center - 2.0 Mi to City Park!

Home in St. Louis

4.92 out of 5 average rating, 180 reviews

Private Oasis w/hot tub

Wonderfully renovated 2 bedroom brick bungalow in highly desirable South city location. This home sits on a double lot, which has been completely renovated, featuring exterior shower with hot and cold, oversized hot tub, stamped concrete, gas fire pit, barbecue pit, and plenty of seating for up to 6 guests. Inside you’ll find home has been completely gut rehabbed featuring exposed brick walls, updated kitchen w/ center island. Two large bedrooms; queen size beds, all new furnishings throughout.

Home in Saint Charles

4.88 out of 5 average rating, 103 reviews

The Cardinal Nest A Cozy Cottage on Historic Main

The Cardinal nest is located directly on the cobblestone streets of St. Charles. the perfect place to lay your head if you are in town for a wedding, work, visiting family and friends or coming for a bike ride on the Katy Trail. The nest has 2 bedrooms, 1 full and 1 queen and will host 4 guests. The sweet little house hosts 2 units with the front unit being this listing and offers a washer and dryer in the unfinished basement. Guests must walk through one of the bedrooms to get to the bathroo

Apartment in Tower Grove South

4.95 out of 5 average rating, 366 reviews

Handcrafted Space One Block from Tower Grove Park

Welcome to Tower Grove South where you can visit like a local in one of St. Louis' most vibrant, walkable, and architecturally significant neighborhoods! This bright, fully restored second floor apartment offers the best mix of historic details with the comfort of modern amenities. Only steps from a variety of local cafes, boutiques, and parks off S Grand Ave! It is also within walking distance of the beautiful Missouri Botanical Gardens and Tower Grove Park; offering popular events all year.

Apartment in St. Louis

4.94 out of 5 average rating, 190 reviews

Historic Victorian Comfort, Safe neighborhood

First, check out all 4 of our private 5 Star listings that creatively combines the old with the new. If one is unavailable, check the others by going to “My Profile” and scrolling down until you see all 4. This Historic building; built in 1896 has changed missions through the years; From church, to merc. Trade, to grocery store; quite the history have graced these walls. You’ll love our safe, Southwest Gardens area; next to the famous “Hill” offers unmatched restaurant, shops, bakeries

Home in Fenton

4.84 out of 5 average rating, 237 reviews

Fenton Oasis

Lovely fully furnished private basement >1800 sq ft single family home. Private heated pool is open and heated, kitchen, bathroom tub/shower, living room with fireplace TV, bedroom with egress full window and 2nd sleeping area. Many free parks with canoeing, hiking and biking trails nearby. Easy access to hwy 44. 270 & hwy 30, -restaurants -minutes from downtown St. Louis and airport. https://www.airbnb.com/highlights/131701267?s=39&unique_share_id=64fb0944-a8c7-40c1-bc83-6e65e70afeaf

Home in Saint Charles

4.94 out of 5 average rating, 139 reviews

🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟

New Carpet! Adorable turn of the century home is located in Midtown St. Charles Historic District and sleeps 7. You won’t want to miss this St. Charles Charmer! Updated, fully stocked kitchen, dining room with Keurig coffee bar, living room w/75" SmartTV and plenty of seating throughout, SmartTV in 2 Bedrooms, 2 full bath, washer & dryer, outdoor gazebo w/table & chairs. Street & driveway parking. Close to area attractions: Historic Main Street, Ameristar Casino, & Lindenwood University.

Home in Saint Charles

4.98 out of 5 average rating, 130 reviews

Charming 2/1 in St Charles Historic Main Street

Come relax and play! Half a block from historic Main Street in City of St Charles. This stay is everything you could want. Cozy, charming, private with outdoor area for seating and dinning table. Off-street parking, laundry. Go shopping in the historic downtown shops, go to concerts, casinos or just stay in and enjoy! Walk to restaurants and the Katy Trail! Come be our guest! Or stay in put and cook the kitchen has everything you need! We are a strictly non smoking stay, inside or outside.

Home in Saint Charles

5 out of 5 average rating, 41 reviews

Caper on Kings

LUXURY 4BD/2BA Cottage with , 4 Seasons Room, GAME ROOM, & outdoor fire pit. You will be close to everything when you stay at this centrally-located place! Minutes form Historic St Charles, Walking distance to French town and local coffee shops, restaurants, and shopping. The high end home has plenty of space for everyone! Cook your favorite dinners in the COMPLETELY REMODELED high end kitchen, enjoy conversations around the table in the all window four seasons room or remodeled game room.

Home in Tower Grove South

4.99 out of 5 average rating, 231 reviews

Spacious Family & Friends House Across From Tower Grove Park

Climb the front steps of a remarkably preserved craftsman period house with its exterior character intact. Inside is a modern space that's been remodeled top to bottom to a high level of quality and style, including a chef's kitchen and formal dining area. The house is the perfect place for large groups and families wanting plenty of space to spread out, relax and spend time together. Very kid friendly with porta cribs, highchairs, strollers and a baby monitor available for your use.

Loft in Saint Charles

4.86 out of 5 average rating, 138 reviews

Main Street Historic Loft

Historic loft centrally located along the St. Charles riverfront, on the north end of Main Street and just south of Frenchtown. Enjoy Frontier Park, shops, restaurants, and night scene - all within walking distance. The newly renovated 2 bedroom and 2 full bathroom apartment can easily accommodate groups of six. The completely updated kitchen has granite countertops, stainless steel appliances, and a dishwasher. Convenient in-house washer and dryer available for extended stays.

Home in South Hampton

5 out of 5 average rating, 28 reviews

Blair's Amazing House Sleeps 10 - 5 Beds - 2 Bath

Bring the family and welcome to Blairs House. Long Stays Welcome! - Stay for 30 days or more and SAVE! - Not available? Check our profile for over 30 listings in the area. 4 Bedrooms with 2 Full Bathrooms - One upstairs and One on the main level. Four Queen Beds and One King Bed. Cozy Living Room Dining Room seating for Eight Kitchen is fully stocked with all the essentials for casual cooking or thanksgiving dinner. Washer & dryer and Game Room located in Lower Level.

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Popular amenities for Clayton vacation rentals

Free parking on premises

Air conditioning

Stay near Clayton's top sights

Washington University in St. Louis34 locals recommend

Delmar Loop142 locals recommend

Saint Louis Zoo579 locals recommend

Saint Louis Art Museum431 locals recommend

The Pageant72 locals recommend

St. Louis Galleria146 locals recommend

Other great vacation rentals in Clayton

Home in Ballwin

4.95 out of 5 average rating, 126 reviews

Private indoor pool & sauna

Home in Ballwin

4.83 out of 5 average rating, 24 reviews

Becky's Oasis-Sleeps 6/3 beds/Ballwin MO

Home in Ballwin

5 out of 5 average rating, 19 reviews

Perfect Getaway 3BR/3BA Home

Home in Saint Charles

4.86 out of 5 average rating, 28 reviews

4BR Victorian Gem in St. Charles

Apartment in St. Louis

4.87 out of 5 average rating, 289 reviews

We do Italian STL style. Perfecto! Enjoy our NBHD!

Home in St. Louis

4.85 out of 5 average rating, 61 reviews

Modern Luxury w/Saltwater Pool / ABODEbucks

Home in Lindenwood Park

4.87 out of 5 average rating, 703 reviews

Centrally Located Family Home - Big Yard & Garage

Home in The Hill

4.93 out of 5 average rating, 88 reviews

Casa Italiana: Cozy home in the heart of The Hill

Quick stats about vacation rentals in Clayton

Total rentals
40 properties
Total number of reviews
1.4K reviews
Family-friendly rentals
20 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Wifi availability
40 properties include access to wifi

Frequently Asked Questions

Are there family-friendly vacation rentals in Clayton?
Clayton has more than 20 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.
How much does it cost to stay in apartment rentals in Clayton?
Experience the best of Clayton with our apartment rentals, starting at about $50 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Do apartment rentals in Clayton have air conditioning?
Absolutely! We offer over 20 apartment rentals with air conditioning in Clayton. Enjoy a tailored experience with all the comforts you desire.
Are there pet-friendly vacation rentals in Clayton?
Four-legged friends are welcome in Clayton. Choose from more than 10 vacation rentals for guests traveling with pets.
Are there vacation rentals with a dedicated workspace in Clayton?
Yes! Work meets play with ease at over 20 vacation rentals in Clayton featuring dedicated workspaces. Stay connected and productive in your home away from home.
Where should I stay in Clayton?
Make yourself at home in Clayton by choosing from our most frequently booked neighborhoods. We have over 310 vacation rentals in Downtown Clayton, and over 310 vacation rentals in Wydown Skinker.
What are the most popular amenities for Apartment Rentals in Clayton?
Enhance your stay in our Apartment Rentals with the most popular amenities: over 20 homes with air conditioning, over 10 homes with free parking, over 20 homes with wifi, over 20 homes with a kitchen, and more. Indulge in the ultimate retreat, tailored to your preferences.
Do apartment rentals in Clayton have a kitchen?
Absolutely! We offer over 20 apartment rentals with a kitchen in Clayton. Enjoy a tailored experience with all the comforts you desire.
Do apartment rentals in Clayton have free parking?
Absolutely! We offer over 10 apartment rentals with free parking in Clayton. Enjoy a tailored experience with all the comforts you desire.
Do apartment rentals in Clayton have wifi?
Absolutely! We offer over 20 apartment rentals with wifi in Clayton. Enjoy a tailored experience with all the comforts you desire.

Destinations to explore