House vacation rentals in Franklin County

Find and book unique houses on Airbnb

Top-rated house rentals in Franklin County

Guests agree: these houses are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

Home in Augusta

5 out of 5 average rating, 74 reviews

Central Luxe 5br Home | Hot Tub & Views | 🥂 🍷

Relax while you overlook the Katy Trail, enjoy incredible views, and are within WALKING distance of Good News Brewery, Mount Pleasant Winery & Augusta Winery. Shuttle services also available! This spacious home is in the heart of wine country. Take some time with your friends, family or partner to unwind and put your worries behind you. This home offers enough room for 12 people to comfortably stay while also creating an intimate ambiance if you wish to enjoy a romantic weekend in wine country.

Guest favorite

Home in Washington

4.92 out of 5 average rating, 111 reviews

Knott House-short walk to downtown/riverfront

This house built in 1906 has classic old world charm with wood floors, tall ceilings, and original mill work. A short walk to restaurants, boutiques, trollies, and the riverfront. Enjoy the wineries, brew houses, and all WashMO has to offer. Home has 3 bedrooms and 1 1/2 baths. There are 2 king beds and a queen along with a queen pullout sofa. The kitchen is newly remodeled and is stocked with everything you need to cook meals. Complimentary bottle of wine awaits you! Wi-Fi /tv w/firestick

Guest favorite

Home in Pacific

4.92 out of 5 average rating, 122 reviews

Pacific Palace, super unique!

The Pacific Palace is unlike any other Airbnb! Located in the heart of downtown Pacific, Missouri - only 2 minutes from Highway 44 and 10 minutes from Purina. This house is an incredible one of a kind treasure with lots of unique features including: outdoor gazebo, Koi pond, all original cedar interior design, two second story balconies, two Jacuzzi tubs (one located in the master bedroom) and so much more!!! Private parking and a gate for added privacy. Just minutes from Six Flags. Book today!

Guest favorite

Home in Sullivan

4.89 out of 5 average rating, 189 reviews

Comfy Miramiguoa Home

A great view of the woods awaits you from the countryside kitchen window and off the back deck. The 2 bedroom house has a warm cozy feel and can accommodate 6 people. It adjoins Meramec State Park boundary, which has hiking trails, river access, fishing and floating. Nearby is Meramec Caverns, Onondaga Cave, antiquing, restaurants, breweries, wineries and small zoos. Within 1 hours drive is St. Louis, the Katy trail for bicycling. Enjoy a relaxing comfy stay where deer are frequently seen.

Guest favorite

Home in Augusta

4.99 out of 5 average rating, 245 reviews

Katy Trail Farmhouse - 3 bd/2.5 bath - Amazing!

DIRECTLY ON THE KATY TRAIL! Quaint 1943 farmhouse on 7 private acres in Missouri wine country - halfway between Klondike Park & the town of Augusta. Loads of farmhouse charm w/ the amenities & comforts of home. Spacious & well-appointed, 3 bedrms/2.5 baths. Walk-in/out or bike-in/out to KATY trail -- the location is perfect. Enjoy a sunset dinner & live music at one of the many wineries – or relax on one of the two screened-in porches & clear your mind. No other place like it in Augusta!

Guest favorite

Home in Washington

4.96 out of 5 average rating, 54 reviews

Charming 1930's cottage home with a beach vibe.

Make a memory in this comfortable 1930's farmhouse loaded with unique art which lends a clean nautical vibe with a touch of Missouri heartland warmth. Perfect for reconnecting with friends and family. Enjoy this fully furnished home and relax. Just a 5 minute drive to the Missouri River and historic downtown where you may enjoy shopping, antiquing, dining, festivals, and wineries. This home sits on a spacious corner lot with plenty of yard for lawn games, a fire pit, and free street parking.

Guest favorite

Home in Beaufort

4.99 out of 5 average rating, 163 reviews

Entire home! Sleeps 8, Pool, Hot tub, Lake, 52 AC

One hour from St. Louis! 30 minutes from Six Flags. Our totally renovated guest house is tucked away on our 52 acre farm with WI-FI and fishing lake. The hot tub is yours to enjoy 24/7, 365 days a year! Our guest house sleeps 8, with 3 bedrooms and a futon. Ambiance with the gas/stone fireplace and an open floor plan. A fully stocked kitchen and large deck with gas grill. 20X40ft fenced, in-ground pool is open for guest use. Floating dock with solar power and firepit will be launched Jan 27

Guest favorite

Home in Union

4.95 out of 5 average rating, 243 reviews

Historic 6 bedroom home. 45 minutes from STL.

Built in the early 1900s, this Victorian home is situated in a quiet neighborhood in downtown Union. Close to several great restaurants, The home is central to some of Missouri’s best attractions. This 6 bedroom home is large enough the whole family can spread out. 8 min from I-44 10 min from Washington 20 min from Six Flags 45 min from the St. Louis Arch, the Zoo, and Busch Stadium. $50 per pet fee. *For pet owners traveling to Purina with over 10 dogs a rate can be discussed.

Guest favorite

Home in Gray Summit

4.88 out of 5 average rating, 149 reviews

Sunset Mountain Privacy Retreat

9 rooms on the main floor with private entrance, kitchen, and covered deck are all yours in this shared property. Host stays in lower level and the only places shared are the laundry room & outside. Great for families and dog owners attending Purina Farms. I allow small birthday & graduation celebrations, baby & bridal showers, meetings & conferences, classes & reunions with a maximum capacity of 20 people or 8 vehicles. Let me help make your special occasion one to remember.

Guest favorite

Home in Washington

4.93 out of 5 average rating, 70 reviews

Downtown Boho Bungalow

Enjoy your stay at this newly remodeled 3 bedroom two bath home. This house sleeps 8 comfortably with a queen size bed in the master bedroom, a queen size bed in the 2nd bedroom and a full size in the 3rd bedroom with a sleeper sofa in the living area. The master bedroom has a full bathroom with a shower and the guest bath has a full bathtub and shower combination. This house has a cozy, large front porch and back deck – only one block from downtown and the Missouri River!

Guest favorite

Home in Villa Ridge

4.77 out of 5 average rating, 239 reviews

Sunny Modern Farmhouse - Pet Friendly Purina Farms

Our Coleman Road farm may look like a quaint older house from the outside, but inside you'll find a stylishly-updated modern farmhouse you'll be excited to spend time in. The rooms are filled with afternoon sunlight, and have been tastefully decorated to provide a tranquil and comfortable retreat. With a spacious living room, two bedrooms, a full bath, and separate kitchen and dining area, the space offers everything you need in a cozy and modern setting.

Guest favorite

Home in Washington

4.99 out of 5 average rating, 137 reviews

*Historical* Aletha-Marie Krog Guest House

Built in 1895, this charming two story historic brick home is located in beautiful downtown Washington, Missouri. Just blocks away from bars, restaurants, art galleries and shopping. Guests will feel right at home with our 3 cozy bedrooms and 2 full bathrooms, a full eat-in kitchen, living room, and four season room. It's been said, many times, that there is a pleasant vibe or feeling to this beautiful old place. It's been around a long time.