House vacation rentals in Little Italy, San Diego

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Top-rated house rentals in Little Italy, San Diego

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite

Home in North Park

4.96 out of 5 average rating, 291 reviews

One-of-a-kind TINY House North Prk Safe.Private

Heart of North Park/Hillcrest San Diego. Light, bright, super clean private & safe. An adorable, cozy tiny house~we welcome happy, chill couples/solo travelers who love laid back travel experience. Real queen bed, COMFY! Full kitchen Private entrance w/easy key pad WiFi/32 inch TV A/C Beach gear Balboa Park/SD Zoo/Beach/Bars/Restaurants VERY walkable Enjoy magical evenings w/twinkle lights & fire table. Wake up to birds singing in the morning, STREET PARKING & Easy Uber/Lyft from

Guest favorite

Home in Golden Hill

4.99 out of 5 average rating, 332 reviews

Golden Hill Tree House

The Golden Hill Tree House is an urban oasis hiding in the branches of two mature trees in the heart of San Diego. While you enjoy elevated privacy you can also treat yourself to a soaker tub with double shower heads or settle down in a cozy reading nook to enjoy a good book! You'll also be walking distance to some amazing restaurants and super close to the best of San Diego, including downtown, the beach and the zoo! It's a perfect place to recharge after a long day of business or pleasure!

Guest favorite

Home in North Park

4.98 out of 5 average rating, 389 reviews

Award-Winning, Family-Friendly 2BR on Balboa Park

★ Condé Nast rated top in SD ★ Luxury 2BR/1BA home w/ AC ★ Across the street from Balboa Park, concerts & sunsets ★ 4 min to Zoo ★ 15 min to Beach ★ 7 min walk to North Park entertainment corridor - breweries, restaurants, cafes, yoga & shops ★ Family-friendly space, crib ★ Easy free street parking ★ Fully remodeled in 2022, professionally designed ★ Fresh artisan coffee, Nespresso ★ 4K TV, Netflix, HBO ★ We welcome people from all backgrounds ★ Security camera at exterior entry (none inside)

Guest favorite

Home in Mission Hills

4.93 out of 5 average rating, 224 reviews

Lionhead - Private Boutique Home

Heated pool, spa, cabana and views. Boutique hotel vibes in San Diego. Palm Springs meets South Beach with a splash of groovy. Location is perfect for Downtown, conventions, shows in town. Highway friendly. Private backyard for bbq, food, drinks and relaxing. Pool is heated with cozy spa to relax and watch the planes take off. Hi speed Wifi, smart TV's, HBO, NFL Package, record player with albums. 19 speakers in the ceilings with connected to your phone for optimal happiness. Plug and play!

Guest favorite

Home in Bunker Hill - Park West

4.9 out of 5 average rating, 114 reviews

Stunning by Little Italy ConventionC Zoo ParkingAC

Stunning Mansion perfect for your family, professionals or group of friends, right by the Convention Center, Little Italy, Balboa Park within minutes of all SD attractions and beaches with the best Amenities and two parking spaces. Old school decor and high-end everything, from the towels and sheets to the appliances and chef's kitchen, will make your experience one to remember. The large living room, games area, kitchen and dining is perfect to create amazing memories, relax and enjoy!!

Guest favorite

Home in North Park

4.95 out of 5 average rating, 116 reviews

Walkable North Park Urban Oasis with Private Yard

A stylish, peaceful, private stay at our North Park craftsman bungalow. Located on a residential street, but very walkable to everything in North park, one of the trendiest neighborhoods in San Diego (walk score of 92). Our casita is a separate guest house located in the back of of our property with it's own entrance and private yard. Enjoy brand new hard wood floors, remodel kitchen, lush bedding, high speed internet and smart TV. 2 off-street parking spots, free laundry, and pets welcome!

Guest favorite

Home in Bunker Hill - Park West

4.95 out of 5 average rating, 428 reviews

Admire Harbor Views from the Porch at a City Gem

Unwind in a cozy colorful casita in this light-filled 1920s Spanish bungalow with Mexican accents and a casual feel.Take a walk into Little Italy for dinner. What’s best, is how close you are to so much, all without needing a car. A very small single car garage is provided, think compact car. Street parking is free but challenging at times. The house is located directly below the incoming flight path. You are encouraged to read the reviews regarding this. Ideal for four or less persons.

Superhost

Home in Downtown San Diego

4.9 out of 5 average rating, 643 reviews

#1 LOCATION - Rare Luxury Home in Downtown

***THE BEST RATED RENTAL IN DOWNTOWN SAN DIEGO*** Location doesn't get better than this! Right in the heart of the lively Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. Just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & Zoo! All the frills: + Prime location! 98/100 Walker Score rating + Private parking + Private Sundeck & Backyard Stay at this modern luxury home for your next trip!

Superhost

Home in Downtown San Diego

4.84 out of 5 average rating, 159 reviews

Little Italy 2BR Loft Near Waterfront & Convention

Discover the heart of San Diego from our spacious loft in Little Italy, the culinary gem of downtown. Perfectly situated for both business and leisure travelers, you're steps away from the waterfront, convention center, and vibrant city life. Embrace the urban experience with convenience at your doorstep, including eclectic bars and restaurants. We provide a white noise machine and earplugs, though the lower floor offers a quieter retreat. Experience the best of city living!

Guest favorite

Home in Downtown San Diego

4.98 out of 5 average rating, 248 reviews

Downtown View - 2 Story House Next to Little Italy

Two story house with 2 living rooms; 3 blocks to Little Italy restaurants, bars, & shops. Near Balboa Park, San Diego Zoo, Gaslamp, Waterfront Park & the Harbor. Museums, restaurants, theaters & nature are all nearby. Located in historic Bankers Hill, next to Interstate 5, near the airport and city center. With 2 living rooms, my house is perfect for travelers needing separate space. One parking spot is available. Extra large vehicles will have to park on the street.

Superhost

Home in Barrio Logan

4.89 out of 5 average rating, 200 reviews

The Pink Casita of Barrio Logan

This quaint home is central to everything San Diego. A stylish experience just minutes from Petco Park & Gaslamp! Barrio Logan, known for its art and culture, has tons of shops and restaurants just blocks away. Little Italy, Banker’s Hill, & Hillcrest are a quick Uber away! A quick 15 min drive from SAN. On site amenities include a private parking space, spacious balcony, dedicated workspace, TV & pool table! This carefully curated home will be yours away from home!

Guest favorite

Home in Downtown San Diego

4.92 out of 5 average rating, 119 reviews

Historic Gem in the Heart of Little Italy!

Welcome to Doma Napoli- A Historic Gem in the Heart of Little Italy! Book now for an amazing opportunity to stay at great unit in Little Italy! This 900 square foot unit has everything you need for a fantastic vacation! Included is an assigned parking space for one vehicle, mini-split AC units, fully equipped kitchen, 2 TVs, washer and dryer, and more! There is one queen bed and two twin beds for your use.