Vacation rentals in Sikeston

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Top-rated vacation rentals in Sikeston

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Cabin in Black River Township

4.98 out of 5 average rating, 66 reviews

Well-Designed Cozy Cabin near lake and hiking

Designed for families as a relaxing spot to get away from the hustle & bustle of life, the "Hillside Hideaway" is a 2 bedroom, 1 bath cabin perched on a hill in southeastern Missouri with a gorgeous sunset view from the screen porch. We have a well-stocked kitchen, laundry, fire pit, and plenty of toys and games for the whole family. It is just a couple of miles to a sandy swimming beach at Lake Wappapello, the boat ramp at Chaonia Landing, and many hiking trails in Lake Wappapello State Park.

Guest favorite

Home in Cobden

4.93 out of 5 average rating, 56 reviews

Wine trail, views, hot tub, pool…

Escape your worries in this spacious, serene retreat. Whether your exploring the local wineries, embarking on a girl’s trips, hiking scenic trails, enjoying a family vacation, or even casting a line on a fishing trip, our home is the perfect destination. After a day of adventure, unwind in the comfort of our well-appointed space. End your day by the pool, soak in the hot tub, or enjoy a campfire. Located just a short distance from Bald Knob Cross. Cameras actively recording at all times.

Guest favorite

Treehouse in Greenville

5 out of 5 average rating, 238 reviews

Hidden couple's treehouse "The Roost" & hot tub

"The Roost" is rustic but not primitive treehouse 2 hrs south of St Louis near Wappapello Lake. Yes it has indoor plumbing & running water. Accommodates two adults, has a fully equipped kitchen and breakfast items are provided for you to cook. Surrounded by thousands of acres of national forest. Observe wildlife sightings from the deck while soaking in the hot tub, sleep comfortably in a queen size pillowtop Serta bed on a Motion Air base, and relax as you enjoy the ambience of the fireplace.

Superhost

Home in Carbondale

4.76 out of 5 average rating, 134 reviews

Brick Estate with pool in Quiet Neighborhood

Large fully furnished 4 BR, 3 BTH house in a beautiful, quiet neighborhood in Carbondale. Private pool & large backyard. Very safe & walkable neighborhood. Inspected and licensed by the City of Carbondale. Carbondale Vacation Rental Unit License Number 24-06. Basement with bar, pool table, ping pong. Complete kitchen with all utensils & cookware. Garden patio w/ Weber grill, tables, chairs, beautiful landscaping, etc. ***Pool is open from Memorial Day through Labor Day***

Guest favorite

Cottage in Marion

4.98 out of 5 average rating, 259 reviews

Lakefront cottage Lake of Egypt -Kayaks, breakfast

SUPER HOSTS 8 years straight/high customer rating/many returning guests. *Lake front lounging area; stone steps into the lake! Lakefront cottage w/ 2 open docks, HUGE screened porch overlooking lake. Fish, swim, kayak off our 2 docks! Sleeps Max 6. Full kitchen, washer/dryer. 2 kayaks. Grill, charcoal, fire pit & firewood. We also supply bread, bacon, milk & farm eggs! Guest Requirements: 3 Night minimum stay. *1 positive review required for booking. No Pets.

Guest favorite

Home in Lost Creek Township

4.87 out of 5 average rating, 90 reviews

Camp Bluegill Lake House

New, modern, and cozy with tons of amenities and activities. Relax in the hot tub overlooking the private lake or lounge on the private beach and watch the kids have fun in the paddle boat. Beautiful, secluded property on 5 acres. Tons of parking and easy in and out access for trailers and covered parking. Minutes from beaches, boat ramps and marinas on beautiful Lake Wappapello. Multiple state parks, trails and recreational activities also within minutes.

Superhost

Home in Goreville

4.8 out of 5 average rating, 10 reviews

New! Modern! Lake House Escape! 5 bedroom

Amazing! Lake House Escape views are abundant from this waterfront lake house! With totally unobstructed views of the water from Living area, your family can kick back and relax as the boats go by. The elegant-yet-casual vacation rental has 5 bedrooms, 3 bathrooms spacious living areas overlooking the Bay, and a modern kitchen. Take out the kayaks and Paddle Boards and explore the shore or lounge on the private peninsula and enjoy peaceful location.

Guest favorite

Cabin in Carbondale

4.97 out of 5 average rating, 145 reviews

Couple's Retreat with HOT TUB

The Couple Retreat is designed solely for one couple- nobody but you and your significant other. It's a place where you can relax, reconnect and rejuvenate. The hot tub is surrounded by trees on the screened in porch. Deer graze in the field by the firepit. This cabin has everything you need to make your stay restful and soothing.

Guest favorite

Home in Farmington

4.97 out of 5 average rating, 32 reviews

Come experience relaxation at Eva’s Retreat LLC.

Newly renovated home that is perfect for families or couples. A great place to relax and unwind after a day of enjoying all the local attractions that farmington has to offer. Such as beautiful wineries, local state parks, and just minutes away from 3 local golf courses. Close enough to everything with the feel of a country setting.

Superhost

Apartment in Makanda

5 out of 5 average rating, 3 reviews

Bluestem Retreat, Apartment G

This one bedroom apartment is perched above the trees on 4 rural acres. The open plan provides ample seating on the leather furnishings. There is a 65" smart TV with fast internet. A full kitchen allows you to prepare meals on the new induction range. The extra large bedroom has a view of the surrounding countryside.