Lake house vacation rentals in South Carolina
Find and book unique lake houses on Airbnb
Top-rated lake house rentals in South Carolina
Guests agree: these lake houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for South Carolina lake house rentals
Waterfront lakehouse rentals
Home in Eutawville
5 out of 5 average rating, 12 reviewsShady Cove on Fountain Lake
Home in Summerton
5 out of 5 average rating, 96 reviewsCheerful 3 bedroom home on the lake
Home in Salem
4.99 out of 5 average rating, 118 reviewsKeowee Key Luxury Condo - Stunning Views!
Home in Seneca
4.99 out of 5 average rating, 186 reviewsLakeside @ Lake Hartwell in Clemson, SC 🐟🌅🚤
Home in Chapin
5 out of 5 average rating, 10 reviewsFamily Ties Lakeside Retreat
Home in Modoc
4.93 out of 5 average rating, 109 reviewsIvy’s Escape (water front) at Lake Thurmond
Home in Summerton
4.95 out of 5 average rating, 81 reviewsUltimate Lake Marion Dream Home W/Pool & Swim Spa
Home in Inman
4.95 out of 5 average rating, 111 reviewsCasa del Lago...Come Relax...You are on Lake Time!
Pet-friendly lake house rentals
Home in Saluda County
5 out of 5 average rating, 37 reviewsLake Murray Paradise/Lakefront/Dock/Wifi/Sunrise
Home in Myrtle Beach
4.91 out of 5 average rating, 163 reviews*Clean *fenced yard * close to intercoastal
Home in Seneca
4.94 out of 5 average rating, 109 reviewsGetaway on Lake Hartwell: Pontoon Rental, Clemson
Home in Hilton Head Island
4.93 out of 5 average rating, 107 reviewsCozy Coastal Chic - Beach, Pickleball, Golf, Pets
Home in Anderson
4.99 out of 5 average rating, 191 reviewsLake Escape
Home in Easley
4.91 out of 5 average rating, 145 reviewsLarge lake house - 15 min to Downtown Greenville
Home in Myrtle Beach
4.87 out of 5 average rating, 215 reviewsCozy Beach Paradise in Ocean Lakes | Outdoor TV
Home in Hilton Head Island
4.9 out of 5 average rating, 128 reviewsFamily Gem ~ FREE Heated Pool ~ Walk to Beach~BBQ
Private lake house rentals
Home in Hilton Head Island
5 out of 5 average rating, 49 reviews6 BR, Sleeps 26, Beach Time
Home in Gilbert
5 out of 5 average rating, 16 reviewsTranquility
Home in Johns Island
5 out of 5 average rating, 21 reviewsCharleston Waterfront Retreat w/ Deep Water Dock
Home in Anderson
4.96 out of 5 average rating, 85 reviewsSunset Point-Best view on Broadway - HOT TUB!
Home in Cross Hill
5 out of 5 average rating, 29 reviewsKristen's Lakeside Retreat with hot tub!
Home in Lexington
5 out of 5 average rating, 21 reviewsSunrise and Sunset on the Lake
Home in Waterloo
4.88 out of 5 average rating, 43 reviewsStillwater
Home in Tamassee
5 out of 5 average rating, 52 reviewsWhitewater Lake Front Cottage
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